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In this reaction, a suitable photosensitizer is excited by irradiation to an excited electronic state, and during deactivation, energy is transferred to surrounding oxygen molecules, where it forms singlet oxygen (Sies 1986)

While there's no peer-reviewed data on why this happens, according to Rob Stransky, president of the telehealth provider NiceRx, this can happen because of how these drugs slow the body's gastric emptying process, or how food moves away from the stomach into the small intestine