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This work was supported by the National 14th Five-Year Plan Key Research and Development Program (2024YFD1300204, 2023YFD1301705), high-end foreign experts from the Ministry of Science and Technology of China (G2023014066L), and the Priority Academic Program Development of Jiangsu Higher Education Institution (PAPD), P.R

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These emerging applications offer researchers opportunities to study senescence contributions to neurodegeneration and develop novel approaches for studying brain aging and neurodegenerative disease mechanisms