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Set aside a consistent time each day (ideally after a meal or first thing in the morning) to try and have a bowel movement

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For optimal tolerance, consider: Starting with a lower dose : Begin with a smaller amount and gradually increase if needed Dividing doses : Taking smaller amounts twice daily rather than a single large dose may improve tolerance Consistency : Taking supplements at the same time daily supports adherence Patients experiencing persistent nausea from GLP-1 therapy might temporarily reduce magnesium supplementation during dose escalation periods, then resume once symptoms stabilise

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