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Disrupting salt bridges by mutating residue Glu515 (E515Q) and Arg502 (R502L) led to impaired autoprocessing and activity (Williams et al., 2009)

TB-500 for Joint Health Research indicates that TB-500 may hold therapeutic potential in the treatment of osteoarthritis, a degenerative joint disease

Disseminated Penicillium marneffei infection in southeast Asia

Supplementing GSH to the cell medium has been shown to aggravate this effect 16