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4.8 Electrolytes (Potassium, Sodium) Physiological Role Electrolytes regulate: Fluid balance Cardiac conduction Neuromuscular function Why GLP-1 Therapy May Influence Electrolytes Electrolyte imbalance may occur secondary to: Persistent vomiting Diarrhoea Reduced fluid intake Rapid weight loss This is most relevant during dose escalation or in patients with ongoing GI symptoms

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NAD+ given by IV can cause temporary flushing, nausea, or chest pressure during the drip, which usually fades after the session

Genetic screen of cold tolerance mutants using EMS L4-stage wild-type (N2) hermaphrodites were mutagenized with 0.02 mM EMS (Fujifilm Wako, 325-81522) for 4 h, being rocked and stirred once every hour