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The peptides dual agonism may also explain its superior potency

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Gradual Tapering: The Gold Standard for GLP-1 Discontinuation Abrupt cessation of GLP-1 therapy increases rebound appetite and rapid weight regain

Published peer-reviewed research has established several mechanisms through which these medications support weight management: they help reduce appetite by acting on hunger signals in the brain, they slow gastric emptying - which promotes a feeling of fullness after meals - and they help regulate post-meal blood sugar responses