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Neither participants nor clinical staff knew which treatment each person received until the study concluded, eliminating potential bias in reporting

These conformational changes are stabilized by additional noncovalent interactions involving the conserved residues, such as the Arg121 making hydrogen bonds with Asp67 to further strengthen the pi-cation interactions involving Trp72, Arg102, and Trp110 (see Figure 4 inset 2)

Efficacy was measured by monitoring changes in glycated hemoglobin (HbA1c) and body weight at week 12

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