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Beyond its role as a direct free radical scavenger, glutathione serves as an indispensable cofactor for a family of powerful detoxifying enzymes

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Under normal conditions, Nrf2 is anchored in the cytosol through its interaction with Kelch-like ECH-associated protein 1 (Keap1), which serves as a substrate adapter protein for an E3 ubiquitin ligase complex (Zhang et al

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