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Some patients may experience mild side effects during the first couple weeks of treatment, such as nausea, decreased appetite, or stomach discomfort

Overexpression of PDHA1 restored SLC7A11 expression, suggesting that SLC7A11 plays a crucial role in mediating PDHA1-regulated cuproptosis resistance (Supplementary Fig

Surgery revealed extensive damage to the large intestine, and the patient did not survive

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