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GLP-1 users should avoid meals and snacks that are deep-fried, high in sugar or saturated fat, and spicy or acidic, since those foods can worsen side effects and work against weight-loss efforts, Snashall said

Clinicians should inform patients and families of this risk before initiating treatment, particularly in individuals with psychiatric or substance use comorbidities

This post examines why the approval matters, how small-molecule GLP-1 agonists compare with peptides, and what the shift means for patent strategy and the pipeline ahead