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Original Article

138,139,140 The regulation of immune responses in the tumor microenvironment depends on different types of host cells, including endothelial cells, mesenchymal stem/stromal cells, tumor-associated fibroblasts (TAFs and CAFs), and tumor-infiltrating immune cells, such as lymphocytes, macrophages, myeloid suppressor cells, and tumor-associated neutrophils

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Understanding what butyrate is, from its molecular structure to its complex production pathways, reveals why maintaining optimal levels through diet alone proves so challenging