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For people with major depressive disorder, a more severe form of depression, one study found that vitamin B12 supplements, along with antidepressants, greatly improved symptoms

The second metabolises methylmalonyl-CoA, which keeps the myelin sheath around nerves intact

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It is needed for the absorption of certain vitamins and nutrients from food we eat such as folic acid and carbohydrates which are needed to keep our nerve system healthy Without the sufficient amount of daily vitamins over time this can lead to deficiency, this takes months or even years to develop