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When semaglutide is less effective, it can lead to poor results, even if you are taking the correct dose

Dropping the weight was a slow, arduous process, although the self-esteem payoff was immediate

[28] [29] Call 999 or go to A&E immediately if you experience: Severe chest pain or symptoms of a serious allergic reaction Severe, sudden vision problems (possible acute angle-closure glaucoma with topiramate) Severe, persistent abdominal pain with or without vomiting (possible pancreatitis) Contact your GP urgently or call NHS 111 if you experience: Persistent nausea, vomiting, or abdominal pain Right upper abdominal pain, fever or jaundice (possible gallbladder disease) Signs of dehydration (dark urine, dizziness, reduced urination) Significant increases in heart rate or palpitations Mood changes, depression, or thoughts of self-harm Symptoms of hypoglycaemia (if diabetic): trembling, sweating, confusion Contact your GP or specialist if: You are considering combining weight-loss medications Current medication is not producing expected results You experience troublesome side effects from prescribed treatments You have obtained medications from unregulated sources You require support with weight management strategies Transparent communication with healthcare professionals ensures safe, effective, and personalised approaches to achieving and maintaining a healthy weight