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The link between GSTs and the MAP kinase pathway provides a rationale as to why in many cases the drugs used to select for resistance are neither subject to conjugation with GSH, nor substrates for GSTs

[DOI] [PMC free article] [PubMed] [Google Scholar] Gonzlez-Arancibia C, Urrutia-Piones J, Illanes-Gonzlez J, Martinez-Pinto J, Sotomayor-Zrate R, Julio-Pieper M, Bravo JA (2019) Do your gut microbes affect your brain dopamine

Oxidative stress, in turn, leads to cell and tissue damage and is therefore a major contributing factor to many chronic diseases

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