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This species has been recorded from India, Bangladesh, Pakistan, Thailand, Japan, China, Australia and Indonesia [18].The infection makes the fish unsuitable for human consumption since it produces black spot disease or ink spot disease in the muscles and visceral organs, causing mortality of fishes and thus resulting in the great economic loss [16, 29]

4.2.16 Trilobatin 4.2.17 Isoacteoside Previous research has indicated that the inflammatory response associated with severe acute pancreatitis (SAP) might be diminished by inhibiting TLR4/NF-B signaling pathway (Wang et al., 2017)

Marso SP, Nauck MA, Monk Fries T, Rasmussen S, Treppendahl MB, Buse JB