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Within the GLP-1 RA cohort, 37% of individuals were treated with liraglutide, 25% with semaglutide, 24% with dulaglutide and 13% with exenatide

The relationship between diabetes and cognitive impairment involves many aspects, including central insulin signal transduction, nerve fiber damage caused by hyperglycemia, neuritis, oxidative stress, bloodbrain barrier damage, vascular neuropathy, changes in the dopaminergic system, and the effects of advanced glycation end products on metabolism and energy (Figure 1)

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