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References Rodriguez PJ, Zhang V, Gratzl S et al

161,162,163,164 Impaired glucose uptake and utilization in regional brain energy-substrate hypometabolism may be one of the earliest hallmarks of AD and suggests a potential avenue for compensating the brain energy deficit in AD dementia with ketones

Key point: The formal list in 21 CFR 216.23 is different from FDAs Category 1 list of nominated substances under evaluation

Vitamin B12 plays a crucial role in energy production, nerve function, and red blood cell formation