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However, targeting the precise step that the tumour requires could reduce wider toxicity and off-target effects, especially in healthy cells that also require glutamine for other pathways

PT-141 is not intended to diagnose, treat, cure, or prevent any disease

When astrocytes undergo glycolysis, glucose is quickly converted into L-lactate, which is then transported out of the cells through monocarboxylate transporters (MCTs)specifically MCT1 and MCT4 on astrocytes and MCT2 on neurons

Ten months later, he lost vision in his other eye, leaving him legally blind