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Headache in the first 1-2 doses sometimes attributed by community sources to vasodilatory effects

17 The increased systemic oxidative stress in disease progression and its association with other oxidative stress-related pathologic conditions were suggested for further studies

The structural modifications of the analogs with the best XO inhibition values, with satisfactory IC 50 values, with changes of the groups in 3CF 3 C 6 H 4 and 4iPrOC 6 H 4 , and variations in the same position, 6, with the H, COOC 2 H 5 , and COOH groups (Figure 13)

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