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More research is needed to study potential short- and long-term risks across a broader population, which is why GLP-1s are generally not recommended for breastfeeding women
Clinical Trial CARMELINA Study with Linagliptin in Patients with Type II Diabetes
Furthermore, after 52 weeks of treatment, the Kansas City Cardiomyopathy Questionnaire clinical summary score (KCCQ-CSS) improved significantly among participants in the tirzepatide arm compared with those in the placebo arm (between-group difference = 6.9 [95% CI 3.310.6]
But that insulin release is glucose-dependent, meaning it ramps up when blood sugar is high and backs off when blood sugar is normal
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