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SKU: 24939343876

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Diacylglycerol and ceramide accumulation Consistent with the above studies, elevated plasma fatty acid concentrations can result in increased intracellular diacylglycerol (DAG) levels, leading to the activation of protein kinase C isoform (PKC-) and PKC- isoforms in skeletal muscles and liver respectively

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We have previously shown, that the hearts of newly diagnosed adult PCD patients were within normal echocardiographic ranges with no signs of structural abnormalities or cardiac hypertrophy the results were though not stratified with regards to genotype 22