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Yamazaki, S., Su, Y., Maruyama, A., Makinoshima, H., Suzuki, J., Tsuboi, M

The nuclear isoform, in particular, is involved in the process of the chromatin condensation, which occurs in the final steps of spermatogenesis and requires the replacement of the majority of histones, with transition proteins and protamines, essential for the stabilization of DNA and condensation of spermatocytes

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For instance, olfactory receptors display non-monotonic dose-response, such that the intensity of ol-factory signal relayed from the receptors drops below its maximum value at high odorant concentrations [12 14]