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It has been studied for its ability to influence sleep regulation, stress response, and endocrine balance through hypothalamic signaling

Perhaps the most compelling argument for ergothioneine's biological importance to humans is the existence of a specific transporter: OCTN1 (SLC22A4)

Cerebral glucose metabolism in patients with chronic mental and cognitive sequelae after a single blunt mild traumatic brain injury without visible brain lesions

El-Amine, R