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Other reported or anticipated side effects based on Phase 2 data and the known pharmacology of the drug class include: Injection site reactions redness, bruising, or mild discomfort at the site of subcutaneous injection Fatigue commonly associated with caloric restriction and rapid weight loss Headache reported with GLP-1 receptor agonists as a class Increased heart rate (tachycardia) a known class effect of GLP-1 receptor agonists

While the flat-rate pricing of compounding pharmacies looks attractive if you lack insurance coverage, you must weigh those savings against many safety concerns

Case reports and case series have documented instances of severe, persistent gastroparesis temporally associated with GLP-1 initiation, with some patients requiring hospitalization for refractory nausea and vomiting