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Here are some more specifics [3]: MT1 comprises a linear chain of 13 amino acids

Subsequent medicinal chemistry efforts reveal that a benzaldehyde warhead can similarly engage C326 to promote potent NSD2 degradation, likely due to the flexibility of the Y390-containing loop near C326

Secondly, it indirectly fosters GSH synthesis to lymphocytes and thereby regulates their proliferation and activation ( Figure 1 )