how do you taper off semaglutide Maintenance: Without Regain How to taper off semaglutide

As of mid-2026, there are no completed clinical trials, no formal safety studies, and no peer-reviewed data on the effects of intentional microdosing of semaglutide or tirzepatide for weight management or metabolic health

Intermittent fasting is not inherently dangerous with semaglutide, but it is often unnecessary because the medication already restricts intake naturally

The medications are quite expensive and insurance will often not cover them after a year

Patients on stable thyroid medication may find their TSH levels trending lower after 8 to 12 weeks of semaglutide, signaling the need for laboratory monitoring