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These tumors and the tumors of the spine itself are major risk factors for spinal stenosis

That is three problems converging into one miserable condition

Given the composite nature of bone tissue and the intricate requirements of bone tissue engineering materials, composite materials have become the preferred choice, offering superior performance compared to single-component materials ( Polymethyl methacrylate (PMMA) bone cement is extensively used in orthopedic surgery, but the high elastic modulus and low biocompatibility have limited further advancements (Zhu et al., 2020

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