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Description

Oxyntomodulin: a cAMP-dependent stimulus of rat parietal cell function via the receptor for glucagon-like peptide- 1 (736)NH2

By amplifying these signals, Wegovy reduces hunger, curbs cravings, and makes it easier for patients to stick to a lower-calorie diet

Future research should develop longitudinal datasets to enable analysis of weight loss and side effects in the context of dosage escalations, while exploring genetic factors, which could then inform how genetics might be leveraged in clinical decision-making at treatment initiation and beyond

V.YemenS.BorowitzM.LiuL.PlappM.SunF.et al (2010)