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Stimulates Insulin Secretion GLP-1 enhances the release of insulin from the pancreas in response to food intake

Regarding water retention specifically , GLP-1 receptor agonists do not typically cause fluid retention

No direct association was found between quality of life and medication dosage, intervention duration, treatment frequency and whether accompanied with lifestyle intervention based on the meta-regression results, see Table 2 ( Tables S17, 18 )

Six months into semaglutide treatment, patients typically report 1015% body weight reduction and improved appetite control