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Other indirect evidence also comes from the coordinated response of enzyme activities and corresponding gene expression that is often observed in response to stress
The Th2 cells release cytokines, specifically IL-4 and IL-13, that instruct B-cells to produce immunoglobulin E (IgE) antibodies specific to that allergen
Reinforces the Extracellular Matrix (ECM) : Enhances skin structure and firmness by supporting the ECM, the "scaffolding" that maintains skin integrity
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