Cognitive manifestations include depression, irritability, and anxiety, while GI manifestations encompass constipation, dysphagia, nausea, and prolonged intestinal transit time (Pfeiffer, 2003
FDA guidance states that compounded drugs should be used only when a patient's medical need can't be met by an FDA-approved drug, or when the FDA-approved version isn't commercially available
From a safety or side effect profile, I think the bigger concern is the side effect profile. The GLP-1s do have nausea and vomiting or gastrointestinal side effects, he said, which are usually more pronounced in the first month or two of therapy
Try: Legumes are a staple of the Mediterranean diet and whole food plant-based eating plans, which have both shown to support heart health due to the fiber and antioxidants they provide, notes Zumpano