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A large population-based study found females with a history of lower genital tract infections were at a 2.01 times higher risk of endometriosis than those without this history 74 , while another population-based retrospective cohort found a 3.02 times greater risk of being diagnosed with endometriosis in females who had previously had pelvic inflammatory disease (pathogenic bacteria spreading from vagina to upper genital tract) 75

These brain repair mechanisms suggest that peptides may not just manage symptoms but actively rebuild neural architecture damaged by chronic depression