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Peptidic exenatide and herbal catalpol mediate neuroprotection via the hippocampal GLP-1 receptor/beta-endorphin pathway

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Finally, a recent network meta-analysis that compared cognitive outcomes with various antidiabetic agents in patients with type 2 diabetes observed that GLP-1RAs ranked second after sodium-glucose cotransporter-2 inhibitors for reducing dementia risk

How These Effects Can Impact the Brain Since your brain relies on a steady supply of nutrients, oxygen, and metabolic balance, the side effects from GLP-1s can lead to: Brain fog and mental fatigue: Often linked to low B vitamins, omega-3 deficiency, and undernourishment, these symptoms can make daily concentration and focus more difficult