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doi: 10.1016/s0167-0115(03)00111-3

A second enzyme, histamine N-methyltransferase (HNMT), handles histamine produced within cells throughout the body

Vlasova AN, Diaz A, Damtie D, Xiu L, Toh TH, Lee JS, et al

Nausea was the most common side effect associated with pramlintide, but it was generally mild to moderate and occurred in less than 10% of participants during the extension phase