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10.1056/NEJMoa2032183 154 YanC.HuW.TuJ.LiJ.LiangQ.HanS

DOI 10.1016/j.xcrm.2025.102214.

Additionally, a separate Phase 2 trial in type 2 diabetes demonstrated up to 82 percent reduction in liver fat content at the 12 mg dose results not matched by any other weight loss medication

The patients who will do best on these medications over the long term are those who use them within a framework that protects lean mass, supports metabolic health, and addresses the behavioural and physiological underpinnings of weight regain