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Protein signals released after macrophages engulf lipid debris prompt fibroblasts to secrete large amounts of Type I collagen
After weight loss with ZEPBOUND treatment during the open-label lead-in period (Week 0 to Week 36), continued treatment with ZEPBOUND from randomization (Week 36) to Week 88 resulted in a statistically significant reduction in body weight compared with placebo (see Table 6)
Skipping doses can cause weight regain and may worsen glucose control in diabetic patients
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