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The most robust genetic association is with the TCF7L2 variant rs7903146 ( Autosomal Dominant Polycystic Kidney Disease (ADPKD): Multiple studies and meta-analyses identify ADPKD as an independent risk factor for PTDM ( 4.2 Modifiable risk factors Obesity and BMI: Pre-transplant obesity is a well-established risk factor ( Pre-Transplant Dysglycemia: Impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) are strong independent predictors of PTDM ( A retrospective study of 597 non-diabetic kidney transplant recipients found that pre-transplant IGT conferred a 3.8-fold increased riska stronger predictor than age alone ( Hypomagnesemia: Low serum magnesium, commonly induced by CNI use, is independently associated with PTDM ( Viral Infections: HCV: Hepatitis C infection increases PTDM risk by 3040% ( CMV: Both symptomatic and asymptomatic CMV infection are associated with increased PTDM risk

For compounded vials, every minute on the counter counts