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Thus, this assumption is considered appropriate when there is reasonable similarity in baseline characteristics and inclusion/exclusion criteria between both trials

High triglycerides are a component of metabolic syndrome, which increases the risk of cardiovascular disease, type 2 diabetes, and fatty liver disease

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Patients planning surgery should discuss tirzepatide with their healthcare team, though recent guidance from the American Society of Anesthesiologists indicates most patients can continue GLP-1 receptor agonists perioperatively, with modifications only for those at high risk of gastrointestinal complications