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ArginaseII promotes melanoma migration and adhesion through enhancing hydrogen peroxide production and STAT3 signaling
is a versatile warrior against allergic adversaries
The phosphorylation state of MLC-2 therefore reflects a dynamic balance between MLCK-mediated phosphorylation and MLCP-mediated dephosphorylation, with increased phosphorylation generating ATP-dependent actomyosin contraction and elevated cytoskeletal tension at the apical junctional complex (Jin and Blikslager, 2020)
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