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How GLP-1s work: Biology made therapeutics GLP-1 is an intestinal hormone released after meals

Contrave (Bupropion/Naltrexone) A combination medication that targets the brains hunger and reward pathways to help control cravings and reduce food intake, Contrave is an FDA-approved oral medication for chronic weight management that combines two active ingredients: bupropion, an antidepressant that also helps reduce appetite, and naltrexone, which is used in the treatment of alcohol and opioid dependence

doi: 10.1016/j.dsx.2017.09.013 29 Yovera-AldanaMVelasquez-RimachiVHuerta-RosarioAMore-YupanquiMDOsores-FloresMEspinozaRet al

Healthy appetite suppression means reduced hunger, smaller portions feeling satisfying, fewer cravings, and less food noise