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Description

LONP1 regulates mitochondrial accumulations of HMGB1 and Caspase-3 in CA1 and PV neurons following status epilepticus

It is dictated by the amino acid sequence

Currently, known 11-HSD1 inhibitors can be categorized into two primary groups: natural inhibitors and chemically synthesized inhibitors

In addition, PYC suppresses adipose differentiation-related protein, which is involved in atherosclerosis development and highly expressed in macrophages (Gu et al., 2008), by inhibiting activator protein-1 (AP-1) and NF-B activities, thereby reducing atherosclerosis (Gu et al., 2008)