Novo Nordisk CSO Mads Krogsgaard Thomsen Obviously, tirzepatide being a GLP-1/GIP agonist will, in my mind, based on data we've seen so far, unlike the combination of AM833 and sema, which is an amylin analogue and a GLP-1 analogue, there will probably be additivity of the GI side effect profiles of the GIP and the GLP-1 components
This distinguishes it from better-known compounds such as semaglutide (Ozempic/Wegovy), which targets only the GLP-1 receptor, and from tirzepatide (Mounjaro/Zepbound), which is a dual GLP-1/GIP agonist
Major sources include: Foods Rich in Vitamin B12 Vitamin B12 is naturally found primarily in animal-based foods, such as: Beef liver and pork liver (the most concentrated sources) Red meat, poultry, and fish Eggs, especially egg yolks Shellfish such as clams and oysters Fatty fish like salmon, tuna, and sardines Dairy products including cows milk, yogurt, and cheese For individuals who follow a vegetarian diet, Vitamin B12-fortified foods can be a helpful choice, such as fortified cereals or fortified soy milk
En cuanto al peso, hubo disminucin significativa en ambos grupos a las 24 y 52 semanas, pero el grupo sin AGLP1 perdi ms peso, 2.3 vs 3.9 kg a las 24 semanas y 2.4 vs 4.8 kg a las 52 semanas