tirzepatide 2024 How the weight loss drug is also helping heart failure patients Tirzepatide (Zepbound) - Obesity treatment

doi: 10.1016/j.diabet.2021.101282 Summary Keywords RYGB, suboptimal long-term outcomes, weight regain, T2D relapse, enteropancreatic hormones Citation Andrade S, Lobato CB, Machado M, Hartmann B, Holst JJ, Almeida RF, Nora M, Monteiro MP, Guimares M and Pereira SS (2025) GLP-1 and GIP may play a role in long-term weight trajectories after gastric bypass

Downstream observations in models include transcriptional changes consistent with enhanced mitochondrial function and lipid utilization

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Changes in the pig small intestinal mucosal glutathione kinetics after weaning