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Wedelolactone inhibits caspase-1/11 activation and reduces IL-1 and gasdermin D levels, thereby alleviating pyroptosis, ferroptosis, and lung injury through glutathione peroxidase-4 (GPX4) mediation [106]

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The increase in these inflammatory markers, along with characteristics of oxidative stress, is commonly associated with lowgrade systemic inflammation

We are currently in an internal evaluation phase, reviewing the published research and running a structured internal protocol with our clinical team