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In clinical trials, people who took semaglutide lost significantly more weight compared to those who were given a placebo (a pill with no medicine in it)

Stool softeners such as docusate sodium (Colace) have minimal evidence supporting their efficacy as monotherapy and are generally not recommended alone for semaglutide-induced constipation

Programs that screen carefully tend to deliver safer results and are less likely to prescribe treatment that isn't appropriate

4, 2026 at 12:25 PM CST | By Charles Herrington and Abigail Ware Lydia Ezell and Erica Wade made their first appearance in court on Wednesday morning