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Cerebral hypoperfusion: a new pathophysiologic concept in multiple sclerosis

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This effect may be mediated by the peroxisome proliferator-activated receptor gamma (PPAR)/retinoid X receptor (RXR) pathway, which directly affects gene expression, or by reducing oxidative stress and modifying the inhibitor of kappa B (I-B)/NF-B pathway [75]

If the question is which has established clinical availability, approved GLP-1 receptor agonists clearly have the advantage