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McKinsey Global Institute projected that broad GLP-1 adoption for eligible obese adults in high-income countries could generate USD 1.8 trillion in cumulative healthcare savings by 2040 through reduced cardiovascular hospitalizations, diabetes complication avoidance, and musculoskeletal disease prevention

New Study Highlights Superiority of Bariatric Surgery Over GLP-1 Medications for Sustained Weight Loss A new real-world study presented at the ASMBS 2025 Annual Meeting compares outcomes between GLP-1 medications (such as semaglutide and tirzepatide) and bariatric surgery

Lee MMY, Kristensen SL, Gerstein HC, McMurray JJV, Sattar N

An outline of the MD simulations performed on the GLP-1R bound to Ex4-L-Ala ( a ), Ex4 ( b ) and Ex4-D-Ala ( c )