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When to Adjust Your Semaglutide Dose or Switch Formulations If headaches persist beyond 4 weeks or become severe enough to interfere with work or sleep, contact your PlexusDx provider to discuss dose timing or reduction options

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Year-1 tirzepatide titration cost (Direct Meds-style monthly pricing): Year-2 maintenance tirzepatide cost (steady at 12.5 mg): Year-1 semaglutide titration cost: What this changes about decision-making: - A "$179/month" headline turns into roughly $3,000 in year one and $3,200 in year two - Brand Wegovy at $500/month direct is $6,000/year