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Glp1r Tie2/ mice were generated by crossing Glp1r fl/fl mice with Tg (Tek-Cre)1Ywa ( Tie2) Cre mice (Jackson Laboratory, 008863) to target endothelial and immune cells in the Tie2 domain, as previously described (25, 26)

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The stated rationale behind the blend is that its components appear in overlapping literatures copper-peptide matrix signaling on one side, repair and angiogenesis peptides on the other

Biopsy of the esophageal mucosa is more difficult than biopsy of gastric or intestinal mucosa and is not commonly performed with the exception of mass lesions