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29 The prototype for this class of compounds is obeticholic acid (OCA), which has been extensively investigated and shown to significantly improve the histological features of MASH, although it can cause side effects such as pruritus and increased low-density lipoprotein (LDL) cholesterol

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While this is beneficial for fat loss, it can also result in insufficient protein consumption, depriving the body of the essential amino acids required for muscle protein synthesis

Open Calculator Tirzepatide Dosage Chart See the standard weekly escalation schedule from 2.5mg through 15mg maintenance and where symptoms typically peak